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1

Gsmodutils: A python based framework for test-driven genome scale metabolic model development

Gilbert, James, Pearcy, Nicole, Norman, Rupert, Millat, Thomas, Winzer, Klaus, King, John, Hodgman, Charlie, Minton, Nigel, Twycross, Jamie, Schwartz, Russell

Journal:

Year:

2019

File:

PDF, 457 KB

2019

2

The role of flagella in Clostridium difficile pathogenicity

Stevenson, Emma, Minton, Nigel P., Kuehne, Sarah A.

Journal:

Trends in Microbiology

Year:

2015

Language:

english

File:

PDF, 1.13 MB

english, 2015

3

The role of toxin A and toxin B in Clostridium difficile infection

Kuehne, Sarah A., Cartman, Stephen T., Heap, John T., Kelly, Michelle L., Cockayne, Alan, Minton, Nigel P.

Journal:

Year:

2010

Language:

english

File:

PDF, 439 KB

english, 2010

4

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

Sebaihia, Mohammed, Wren, Brendan W, Mullany, Peter, Fairweather, Neil F, Minton, Nigel, Stabler, Richard, Thomson, Nicholas R, Roberts, Adam P, Cerdeño-Tárraga, Ana M, Wang, Hongmei

Journal:

Nature Genetics

Year:

2006

Language:

english

File:

PDF, 617 KB

english, 2006

5

A simple procedure for gel electrophoresis and Northern blotting of RNA

Goda, Sayed K., Minton, Nigel P.

Journal:

Nucleic Acids Research

Year:

1995

Language:

english

File:

PDF, 999 KB

english, 1995

6

Complete Genome Sequence of the Nonpathogenic Soil-Dwelling Bacterium Clostridium sporogenes Strain NCIMB 10696

Kubiak, Aleksandra M., Poehlein, Anja, Budd, Patrick, Kuehne, Sarah A., Winzer, Klaus, Theys, Jan, Lambin, Philip, Daniel, Rolf, Minton, Nigel P.

Journal:

Genome Announcements

Year:

2015

Language:

english

File:

PDF, 158 KB

english, 2015

7

Enhanced solvent production by metabolic engineering of a twin-clostridial consortium

Wen, Zhiqiang, Minton, Nigel P., Zhang, Ying, Li, Qi, Liu, Jinle, Jiang, Yu, Yang, Sheng

Journal:

Metabolic Engineering

Year:

2016

Language:

english

File:

PDF, 1.79 MB

english, 2016

8

Metabolic engineering of Clostridium autoethanogenum for selective alcohol production

Liew, Fungmin, Henstra, Anne M., Kӧpke, Michael, Winzer, Klaus, Simpson, Sean D., Minton, Nigel P.

Journal:

Metabolic Engineering

Year:

2017

Language:

english

File:

PDF, 1.92 MB

english, 2017

9

13C-assisted metabolic flux analysis to investigate heterotrophic and mixotrophic metabolism in Cupriavidus necator H16

Alagesan, Swathi, Minton, Nigel P., Malys, Naglis

Journal:

Year:

2018

Language:

english

File:

PDF, 2.54 MB

english, 2018

10

Upscaling Diffusion Through First-Order Volumetric Sinks: A Homogenization of Bacterial Nutrient Uptake

Dalwadi, Mohit P., Wang, Yanming, King, John R., Minton, Nigel P.

Journal:

SIAM Journal on Applied Mathematics

Year:

2018

Language:

english

File:

PDF, 922 KB

english, 2018

11

A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics

Daniel I. R. Spencer, Lynda Robson, Des Purdy, Nick R. Whitelegg, N. Paul Michael, Jeetendra Bhatia, Surinder K. Sharma, Anthony R. Rees, Nigel P. Minton, Richard H. J. Begent, Kerry A. Chester

Journal:

Year:

2002

Language:

english

File:

PDF, 855 KB

english, 2002

12

Anaerobe-mediated anticancer gene therapy

Mattin Brown, J. Lemmon Marilyn, H. Elwell James, E. Fox Mary, P. Minton Nigel

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

1994

Language:

english

File:

PDF, 155 KB

english, 1994

13

Gene transfer into Clostridium difficile CD630 and characterisation of its methylase genes

Michael Herbert, Triona A. O’Keeffe, Des Purdy, Michael Elmore, Nigel P. Minton

Journal:

FEMS Microbiology Letters

Year:

2003

Language:

english

File:

PDF, 398 KB

english, 2003

14

Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier

Des Purdy, Triona A. T. O'Keeffe, Michael Elmore, Mike Herbert, Anne McLeod, Monika Bokori-Brown, Anna Ostrowski, Nigel P. Minton

Journal:

Molecular Microbiology

Year:

2002

Language:

english

File:

PDF, 348 KB

english, 2002

15

The analysis ofpara-cresol production and tolerance inClostridium difficile027 and 012 strains

Lisa F Dawson, Elizabeth H Donahue, Stephen T Cartman, Richard H Barton, Jake Bundy, Ruth McNerney, Nigel P Minton, Brendan W Wren

Journal:

BMC Microbiology

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

16

High level expression of a heterologous protein inLactobacillus plantarumand its effect on the persistence of the recombinant strain in silage

Jane E. Rixon, Richard Sharp, Anthony G. O'Donnell, Geoffrey P. Hazlewood, John K. Brehm, Nigel P. Minton, Harry J. Gilbert

Journal:

Biotechnology Letters

Year:

1995

Language:

english

File:

PDF, 386 KB

english, 1995

17

Molecular cloning and nucleotide sequence determination of theBacillus stearothermophilusNCA 1503 superoxide dismutase gene and its overexpression inEscherichia coli

John K. Brehm, Steve P. Chambers, Kevin J. Brown, Tony Atkinson, Nigel P. Minton

Journal:

Applied Microbiology and Biotechnology

Year:

1991

Language:

english

File:

PDF, 741 KB

english, 1991

18

Cloning sequencing and over-expression ofEscherichia colimalate dehydrogenase

David J. Nicholls, Nigel P. Minton, Tony Atkinson, Trichur K. Sundaram

Journal:

Applied Microbiology and Biotechnology

Year:

1989

Language:

english

File:

PDF, 623 KB

english, 1989

19

Plasmid pMTL153: a high copy number version of pAT153 and its use to obtain high expression of thePseudomonascarboxypeptidase G2gene

Steve P. Chambers, Sue E. Prior, Rachell A. Evans, Roger F. Sherwood, Nigel P. Minton

Journal:

Applied Microbiology and Biotechnology

Year:

1988

Language:

english

File:

PDF, 624 KB

english, 1988

20

Introduction of genes for leucine biosynthesis fromClostridium pasteurianumintoC. acetobutylicumby cointegrate conjugal transfer

John D. Oultram, Hazel Peck, John K. Brehm, Daphne E. Thompson, Tracy J. Swinfield, Nigel P. Minton

Journal:

Molecular Genetics and Genomics

Year:

1988

Language:

english

File:

PDF, 405 KB

english, 1988

21

Proposed Topology of the Glucitol Permeases ofEscherichia coliandClostridium acetobutylicum

Jonathan Reizer, Wilfrid J. Mitchell, Nigel Minton, John Brehm, Aiala Reizer, Milton H. Saier, Jr.

Journal:

Current Microbiology

Year:

1996

Language:

english

File:

PDF, 84 KB

english, 1996

22

Multiple orphan histidine kinases interact directly with Spo0A to control the initiation of endospore formation in Clostridium acetobutylicum

Elisabeth Steiner, Angel E. Dago, Danielle I. Young, John T. Heap, Nigel P. Minton, James A. Hoch, Michael Young

Journal:

Molecular Microbiology

Year:

2011

Language:

english

File:

PDF, 909 KB

english, 2011

23

Recent advances in the genetics of the clostridia

Michael Young, Nigel P. Minton, Walter L. Staudenbauer

Journal:

FEMS Microbiology Letters

Year:

1989

Language:

english

File:

PDF, 1.82 MB

english, 1989

24

Cloning and nucleotide sequences of the mdh and sucD genes from Thermus aquaticus B

David J. Nicholls, Trichur K. Sundaram, Tony Atkinson, Nigel P. Minton

Journal:

FEMS Microbiology Letters

Year:

1990

Language:

english

File:

PDF, 388 KB

english, 1990

25

Genetic characterisation of the botulinum toxin complex of Clostridium botulinum strain NCTC 2916

Ian Henderson, Sarah M Whelan, Tom O Davis, Nigel P Minton

Journal:

FEMS Microbiology Letters

Year:

1996

Language:

english

File:

PDF, 676 KB

english, 1996

26

Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI-GalR family of repressor proteins

Sayed K Goda, Omima Eisa, Muhammad Akhter, Nigel P Minton

Journal:

FEMS Microbiology Letters

Year:

1998

Language:

english

File:

PDF, 456 KB

english, 1998

27

Chemotherapeutic tumour targeting using clostridial spores

Nigel P Minton, Margaret L Mauchline, Marylin J Lemmon, John K Brehm, Mary Fox, N.Paul Michael, Amato Giaccia, J.Martin Brown

Journal:

FEMS Microbiology Reviews

Year:

1995

Language:

english

File:

PDF, 649 KB

english, 1995

28

Editorial

Peter Dürre, Nigel P. Minton, E. Terry Papoutsakis, David R. Woods

Journal:

FEMS Microbiology Reviews

Year:

1995

Language:

english

File:

PDF, 67 KB

english, 1995

29

Innovation: Clostridia in cancer therapy

Minton, Nigel P.

Journal:

Nature Reviews Microbiology

Year:

2003

Language:

english

File:

PDF, 551 KB

english, 2003

30

Disruption of the acetate kinase (ack) gene ofClostridium acetobutylicumresults in delayed acetate production

Wouter Kuit, Nigel P. Minton, Ana M. López-Contreras, Gerrit Eggink

Journal:

Applied Microbiology and Biotechnology

Year:

2012

Language:

english

File:

PDF, 1.78 MB

english, 2012

31

Chemotherapeutic tumour targeting using clostridial spores

Nigel P Minton, Margaret L Mauchline, Marylin J Lemmon, John K Brehm, Mary Fox, N.Paul Michael, Amato Giaccia, J.Martin Brown

Journal:

FEMS Microbiology Reviews

Year:

1995

Language:

english

File:

PDF, 659 KB

english, 1995

32

Editorial

Peter Dürre, Nigel P. Minton, E. Terry Papoutsakis, David R. Woods

Journal:

FEMS Microbiology Reviews

Year:

1995

Language:

english

File:

PDF, 68 KB

english, 1995

33

The development of Clostridium difficile genetic systems

Nigel Minton, Glen Carter, Mike Herbert, Triona O’Keeffe, Des Purdy, Mike Elmore, Anna Ostrowski, Oliver Pennington, Ian Davis

Journal:

Year:

2004

Language:

english

File:

PDF, 298 KB

english, 2004

34

The diverse sporulation characteristics of Clostridium difficile clinical isolates are not associated with type

David A. Burns, John T. Heap, Nigel P. Minton

Journal:

Year:

2010

Language:

english

File:

PDF, 749 KB

english, 2010

35

Nucleotide Sequence of the Gene Coding for Proteolytic (Group I) Clostridium botulinum Type F Neurotoxin: Genealogical Comparison with other Clostridial Neurotoxins

Michael J. Elmore, Roger A. Hutson, Matthew D. Collins, Nicola J. Bodsworth, Sarah M. Whelan, Nigel P. Minton

Journal:

Systematic and Applied Microbiology

Year:

1995

Language:

english

File:

PDF, 874 KB

english, 1995

36

Array comparative hybridisation reveals a high degree of similarity between UK and European clinical isolates of hypervirulentClostridium difficile

Gemma L Marsden, Ian J Davis, Victoria J Wright, Mohammed Sebaihia, Ed J Kuijper, Nigel P Minton

Journal:

Year:

2010

Language:

english

File:

PDF, 6.81 MB

english, 2010

37

The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene

Daphne E. THOMPSON, John K. BREHM, John D. OULTRAM, Tracy-Jane SWINFIELD, Clifford C. SHONE, Tony ATKINSON, Jack MELLING, Nigel P. MINTON

Journal:

Year:

1990

Language:

english

File:

PDF, 975 KB

english, 1990

38

The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene

Sarah M. WHELAN, Michael J. ELMORE, Nicola J. BODSWORTH, Tony ATKINSON, Nigel P. MINTON

Journal:

Year:

1992

Language:

english

File:

PDF, 1.08 MB

english, 1992

39

Genetic characterisation of the botulinum toxin complex of Clostridium botulinum strain NCTC 2916

Ian Henderson, Sarah M Whelan, Tom O Davis, Nigel P Minton

Journal:

FEMS Microbiology Letters

Year:

1996

Language:

english

File:

PDF, 716 KB

english, 1996

40

In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein

N.Paul Michael, Kerry A. Chester, Roger G. Melton, Lynda Robson, William Nicholas, Joan A. Boden, R.Barbara Pedley, Richard H.J. Begent, Roger F. Sherwood, Nigel P. Minton

Journal:

Immunotechnology

Year:

1996

Language:

english

File:

PDF, 1.10 MB

english, 1996

41

The emergence of ‘hypervirulence’ in Clostridium difficile

Stephen T. Cartman, John T. Heap, Sarah A. Kuehne, Alan Cockayne, Nigel P. Minton

Journal:

International Journal of Medical Microbiology

Year:

2010

Language:

english

File:

PDF, 355 KB

english, 2010

42

Release of TcdA and TcdB from Clostridium difficile cdi 630 is not affected by functional inactivation of the tcdE gene

Alexandra Olling, Sophie Seehase, Nigel P. Minton, Helma Tatge, Saskia Schröter, Saskia Kohlscheen, Andreas Pich, Ingo Just, Ralf Gerhard

Journal:

Microbial Pathogenesis

Year:

2012

Language:

english

File:

PDF, 897 KB

english, 2012

43

The ClosTron: A universal gene knock-out system for the genus Clostridium

John T. Heap, Oliver J. Pennington, Stephen T. Cartman, Glen P. Carter, Nigel P. Minton

Journal:

Journal of Microbiological Methods

Year:

2007

Language:

english

File:

PDF, 1.07 MB

english, 2007

44

A modular system for Clostridium shuttle plasmids

John T. Heap, Oliver J. Pennington, Stephen T. Cartman, Nigel P. Minton

Journal:

Journal of Microbiological Methods

Year:

2009

Language:

english

File:

PDF, 334 KB

english, 2009

45

The ClosTron: Mutagenesis in Clostridium refined and streamlined

John T. Heap, Sarah A. Kuehne, Muhammad Ehsaan, Stephen T. Cartman, Clare M. Cooksley, Jamie C. Scott, Nigel P. Minton

Journal:

Journal of Microbiological Methods

Year:

2010

Language:

english

File:

PDF, 626 KB

english, 2010

46

Sporulation studies in Clostridium difficile

David A. Burns, Nigel P. Minton

Journal:

Journal of Microbiological Methods

Year:

2011

Language:

english

File:

PDF, 252 KB

english, 2011

47

Clostridium difficile spore germination: an update

David A. Burns, John T. Heap, Nigel P. Minton

Journal:

Research in Microbiology

Year:

2010

Language:

english

File:

PDF, 116 KB

english, 2010

48

Selection of novel TB vaccine candidates and their evaluation as DNA vaccines against aerosol challenge

Julia Vipond, Richard Vipond, Emma Allen-Vercoe, Simon O. Clark, Graham J. Hatch, Karen E. Gooch, Joanna Bacon, Toby Hampshire, Helen Shuttleworth, Nigel P. Minton, Karen Blake, Ann Williams, Philip D

Journal:

Year:

2006

Language:

english

File:

PDF, 219 KB

english, 2006

49

Development of an integrative vector for the expression of antisense RNA in Clostridium difficile

Adam P. Roberts, Claire Hennequin, Mike Elmore, Anne Collignon, Tuomo Karjalainen, Nigel Minton, Peter Mullany

Journal:

Journal of Microbiological Methods

Year:

2003

Language:

english

File:

PDF, 302 KB

english, 2003

50

Cloning, expression and evaluation of a recombinant sub-unit vaccine against Clostridium botulinum type F toxin

Jane L. Holley, Mike Elmore, Margaret Mauchline, Nigel Minton, Richard W. Titball

Journal:

Year:

2000

Language:

english

File:

PDF, 613 KB

english, 2000